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Made in Germany Pharmaceutical-grade GMP
Patented actives Clinical data. Proven absorption.
★★★★★ 4.8 Average Rating Based on verified reviews
90-day guarantee Try it risk-free
Multi-ingredient by design Biology works in systems
Made in Germany Pharmaceutical-grade GMP
Patented actives Clinical data. Proven absorption.
★★★★★ 4.8 Average Rating Based on verified reviews
90-day guarantee Try it risk-free
Multi-ingredient by design Biology works in systems

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CELLARO CORE

The Complete 2-2-2 Longevity Routine.

One coordinated system. Covers all 12 Hallmarks of Aging.

VITALIZE AM ¡ RENEW PM ¡ RESET Monthly

Aging is interconnected - and most supplement stacks are not. Cellaro Core combines three clinically formulated products into one routine: morning energy support, nightly repair, and a monthly cellular reset. Complete coverage without overlaps, stacking, or guesswork.

  • Morning energy & focus: VITALIZE (AM) supports NADâē and sirtuin activity for steadier daytime energy and clear focus
  • Nightly repair & resilience: RENEW (PM) supports autophagy, mitochondrial health, and overnight recovery
  • Monthly cellular reset: RESET delivers a short senolytic pulse to support cellular clean-up and renewal
Monthly Routine Most popular
1,657 kr 1,950 kr / month ¡ skip or cancel anytime
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1 Month Supply
1,950 kr ¡ VITALIZE + RENEW + RESET ¡ one-time
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Made in Germany ¡ GMP certified ¡ Third-party lab tested ¡ Vegan ¡ Gluten-free

There are 12 hallmarks of aging — interconnected biological processes that shape how we age. Most supplement routines target one or two in isolation, leaving gaps and creating overlap between unrelated products.

Cellaro Core is a coordinated system designed to address all 12: VITALIZE (AM) supports NADâē and sirtuin activity for daytime energy and focus, RENEW (PM) supports nightly repair, autophagy, and balanced inflammatory signaling, and RESET (Monthly) delivers a short senolytic pulse to support cellular clean-up and renewal.

Together, the three formulas form a single routine — complete coverage without overlapping ingredients, unnecessary pill burden, or guesswork. Built for consistency and measurable progress over time.

The 2-2-2 routine: a simple daily habit with a short monthly reset. Clear timing, clear roles, minimal complexity.

Morning - 2 capsules: Take VITALIZE in the morning or with your first meal to support NADâē and daytime energy.

Evening - 2 capsules: Take RENEW with dinner or before bed to support overnight repair and autophagy.

Monthly RESET - 2 days: 4 capsules per day for 2 consecutive days each month — 2 capsules in the morning and 2 in the evening.

Build the habit: Results compound with consistency. Take VITALIZE and RENEW at the same times each day, and schedule your 2-day RESET pulse in advance. Cellaro Core is designed for steady, durable change over weeks to months.

If pregnant, nursing, under 18, or taking medication, consult your healthcare professional before use. Food supplement — not a substitute for a varied diet and healthy lifestyle. Do not exceed the recommended daily dose. RESET is designed to be taken as a short pulse — do not take RESET daily.

Morning ¡ Cellular Energy

VITALIZE (AM) - UtheverÂŽ NMN, ApiAgeâ„ĸ apigenin, resveratrol, pterostilbene, TMG

Supports the NADâē cycle and sirtuins for steady daytime energy and clear focus

A clinically studied combination designed to support NADâē levels and sirtuin activity, helping sustain energy, focus, and metabolic efficiency throughout the day.

Evening ¡ Cellular Repair

RENEW (PM) - Spermidine, LongvidaÂŽ curcumin, EGCG, astaxanthin

Supports autophagy, mitochondrial resilience, and balanced inflammatory signaling overnight

A nightly formula designed to support your body's natural repair processes — including autophagy and mitochondrial health — while helping balance everyday inflammatory signaling.

Monthly ¡ Cellular Reset

RESET - QuercefitÂŽ quercetin phytosome, fisetin, luteolin synergy

A short 2-day senolytic pulse to support cellular clean-up and tissue renewal

Three complementary flavonoids at clinically researched doses, taken as a focused monthly pulse to support the body's natural clearance of senescent cells while sparing healthy tissue.

Learn more on the Ingredient Overview page.

Free shipping on all orders.

90-day money-back guarantee. If you are not satisfied, email hello@cellaro.com within 90 days of delivery and we will refund one pouch from your first order. No return required.

Subscriptions ship monthly and can be paused or cancelled anytime from your account.

Designed around the 12 Hallmarks of Aging framework ¡ UtheverŽ, LongvidaŽ and QuercefitŽ are registered trademarks of their respective owners.

CORE PDP — Trust Bar
12 Hallmarks of Aging Every formula targets a recognized driver of cellular aging
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500+ Studies Every ingredient grounded in peer-reviewed research
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12 Ingredients. One System. Complete coverage, no gaps, no overlap
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Engineered Together Better value than sourcing each ingredient separately
âœĻ
One Routine. Three Formulas. VITALIZE AM · RENEW PM · RESET Monthly
12 Hallmarks of Aging Every formula targets a recognized driver of cellular aging
âœĻ
500+ Studies Every ingredient grounded in peer-reviewed research
âœĻ
12 Ingredients. One System. Complete coverage, no gaps, no overlap
âœĻ
Engineered Together Better value than sourcing each ingredient separately
âœĻ
One Routine. Three Formulas. VITALIZE AM · RENEW PM · RESET Monthly
âœĻ
12 Hallmarks of Aging Every formula targets a recognized driver of cellular aging
âœĻ
500+ Studies Every ingredient grounded in peer-reviewed research
âœĻ
12 Ingredients. One System. Complete coverage, no gaps, no overlap
âœĻ
Engineered Together Better value than sourcing each ingredient separately
âœĻ
One Routine. Three Formulas. VITALIZE AM · RENEW PM · RESET Monthly
âœĻ

The Cellaro System

Aging is interconnected. Your routine should be too.

The 12 hallmarks of aging are interconnected, so Cellaro's ingredients are chosen to work together.

The Core Routine addresses all 12 in one simple system that's easy to maintain.

No guesswork. No overlap. No gaps.

Explore the 12 Hallmarks
The 12 hallmarks of aging, mapped to VITALIZE, RENEW, and RESET
CORE PDP — Complete, Not Complicated (2-2-2 Routine)
The Cellaro System

Complete, not complicated.

The Cellaro 2-2-2 Routine

Cellaro VITALIZE, RENEW, and RESET pouches
Vitalize
2 capsules AMEnergy
Renew
2 capsules PMRepair
Reset
2 days / monthSenolytic Reset
CORE PDP — Complete, Not Costly
The Math

Complete, not costly.

Twelve research-backed ingredients, sourced separately, would cost more than double. And you'd still be left to figure out the doses, the timing, and the stacking yourself.

Sourcing it yourself
â‚Ŧ359 / month

12 separate supplements, 12 separate bottles, 12 sets of doses and timing to keep track of.

Best value
Cellaro VITALIZE, RENEW, and RESET pouches
The Cellaro Core system
â‚Ŧ175 / month

The same 12 ingredients, pre-dosed and pre-paired into one simple AM / PM / monthly routine.

See the full price breakdown
Sourcing it yourself
Morning (≈ Vitalize)
NMNâ‚Ŧ70
Resveratrolâ‚Ŧ47
Apigeninâ‚Ŧ24
Pterostilbeneâ‚Ŧ17
TMGâ‚Ŧ17
Subtotalâ‚Ŧ175
Evening (≈ Renew)
Curcumin (Longvida)â‚Ŧ39
Spermidineâ‚Ŧ17
Astaxanthinâ‚Ŧ12
EGCGâ‚Ŧ9
Subtotalâ‚Ŧ77
Monthly (≈ Reset)
Fisetinâ‚Ŧ83
Quercetinâ‚Ŧ15
Luteolinâ‚Ŧ9
Subtotalâ‚Ŧ107
Total≈ â‚Ŧ359 / month
The Cellaro Core system
Vitalize · AM NMN, resveratrol, apigenin, pterostilbene, TMG — for energy and NAD+ support.
Renew · PM Spermidine, curcumin, EGCG, astaxanthin — for overnight cellular repair.
Reset · Monthly Quercetin, fisetin, luteolin — a 2-day senolytic pulse, once a month.
Totalâ‚Ŧ175 / month

DIY pricing reflects the cost of sourcing each ingredient individually at its commonly recommended daily dose from reputable single-ingredient suppliers (incl. DoNotAge, Double Wood, ProHealth, NOW Foods), converted to EUR. Figures are estimates for illustrative comparison and may vary by retailer, region, and exchange rate.

PDP - Track Your Progress
The Data

Track your progress.

Once your routine is in place, here's how to start watching it work, in your data and your bloodwork.

What to look for, and how to measure change over time.

Checking morning readiness on a smartwatch
Wearables
Blood tests
What to measure
Wearables
  • HRV (nightly)
  • Resting heart rate
  • Sleep quality (efficiency and deep-sleep minutes)
  • Readiness / recovery score
Blood tests
  • NAD+ (whole blood)
  • hs-CRP (inflammation)
  • HOMA-IR (insulin sensitivity)
  • A1c (3-month glucose)
  • TG/HDL ratio (metabolic health)
When to measure
Wearables
  • Baseline: week 0 (7-day average)
  • First signs: week 4
  • Best read: after 3 months
Blood tests
  • Baseline: week 0
  • NAD+: 4-8 weeks
  • Other markers: 4-6+ months

These are general guidelines for noticing change over time, not medical advice. Speak with your doctor before starting any new testing routine, especially if you take medication or have an existing health condition.

CORE PDP - Our Ingredients
The Formulas

Our Ingredients

Clinically studied. Backed by science.

Uthever NMN molecular structure illustration Vitalize ¡ AM

UtheverÂŽ NMN

Directly raises NAD+ levels, the molecule your cells rely on for energy production and repair. Clinically studied, over 99% pure.

Explore
Spermidine sourced from wheat germ Renew ¡ PM

Spermidine

Drives autophagy, your body's natural process for clearing and renewing damaged cells, supporting long-term cellular resilience.

Explore
Longvida curcumin root Renew ¡ PM

LongvidaÂŽ Curcumin

Sustained anti-inflammatory support that helps create the right conditions for overnight repair and mitochondrial renewal.

Explore
Quercetin sourced from apples Reset ¡ Monthly

QuercefitÂŽ Quercetin

A phytosome form of quercetin built for significantly higher absorption. Works alongside fisetin to support healthy inflammatory and oxidative balance.

Explore
CORE PDP - FAQ
Questions

Frequently asked questions

Straightforward answers about how the Cellaro Core works, what to expect, and how it fits into your routine.

The Cellaro Core is a structured longevity routine built around the 12 Hallmarks of Aging. It combines three complementary formulas that work together as one coordinated system.

VITALIZE (AM) supports NAD+ levels, cellular energy, and daytime resilience. RENEW (PM) supports autophagy, mitochondrial health, and overnight cellular repair. RESET (Monthly) is a short, focused two-day pulse that helps clear senescent cells.

Rather than three isolated supplements, the Core is timed around your circadian rhythm and designed for consistency and long-term progress.
Cellaro is not a drug, and it does not stop aging. It is designed to support healthspan, the number of years you spend feeling well, by supporting the cellular pathways linked to the 12 Hallmarks of Aging.

As we age, NAD+ declines, inflammation rises, and damaged cells accumulate. The Core addresses these three shifts directly. VITALIZE supports NAD+ and daytime cellular energy, RENEW supports nightly repair and inflammation balance, and RESET helps clear the senescent cells that build up over time.
Your biology runs on a circadian clock. During the day, your cells prioritize energy and resilience. At night, they shift toward repair and cleanup.

Splitting VITALIZE (AM) and RENEW (PM) lets each formula support what your cells are already doing at that time of day. It also keeps your daily pill count low and makes the routine easier to stick to.
Senolytics, the compounds that help clear damaged, senescent cells, work best when used selectively rather than every day.

RESET is taken for two consecutive days each month so it can target dysfunctional cells while sparing healthy tissue. For most people, one pulse a month is enough. During higher-stress periods, some choose a second pulse around days 15 to 16, within label guidance.
Sourcing all twelve ingredients in the Core individually, at comparable doses, would cost roughly EUR 359 a month and leave you managing twelve separate bottles, doses, and timings.

The Cellaro Core brings all twelve into one coordinated AM, PM, and monthly routine for EUR 175 a month, dosed in the ratios used in our formulas. Same ingredients, far less guesswork, far fewer bottles.
Most people notice early signs, like steadier energy and better sleep, within the first four weeks. For meaningful cellular-level change, we recommend a consistent three-month commitment as a starting point.

You can track progress two ways. With a wearable, HRV, resting heart rate, and sleep quality typically shift first, often by week four. With bloodwork, NAD+ can be retested at four to eight weeks, with markers like hs-CRP and HOMA-IR best checked after three to six months.
Yes. The Core is designed to be flexible.

You can adjust timing during travel, illness, or high-stress periods. Consistency over time matters more than daily perfection.

For VITALIZE, most people start with two capsules a day. Once you have found what feels right, some adjust to one capsule a day depending on training load, stress, sleep, and lifestyle, while others continue with two.

For RESET, most people follow one two-day pulse a month, with some adding a second pulse during higher-stress months.

If you miss a day, simply continue as planned. There is no need to double up. The routine is meant to adapt to your life, not the other way around.
The Core is formulated for healthy adults and is not appropriate during pregnancy or breastfeeding. If you have a medical condition or take prescription medicines, especially anticoagulants or medicines that affect lipid levels, speak with your doctor before starting. Always check the label for allergens and excipients.

Longevity Insights

Cellaro CORE - Clinical References

Key clinical studies and references

Cellular aging and senescence

  1. Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nature Reviews Molecular Cell Biology. 2007;8(9):729 to 740. View on PubMed
  2. Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. The Journals of Gerontology: Series A. 2014;69(Suppl 1):S4 to S9. View on PubMed
  3. Childs BG, et al. Senescent cells: an emerging target for diseases of ageing. Nature Reviews Drug Discovery. 2017;16(10):718 to 735. View on PubMed

NAD+ biology and energy (VITALIZE)

  1. Imai S-I, Guarente L. NAD+ and sirtuins in aging and disease. Trends in Cell Biology. 2014;24(8):464 to 471. View on PubMed
  2. Nakahata Y, Sahar S, Astarita G, et al. Circadian control of the NAD+ salvage pathway by CLOCK–SIRT1. Science. 2009;324(5927):654 to 657. View Study
  3. Ramsey KM, Yoshino J, Brace CS, et al. Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science. 2009;324(5927):651 to 654. View Study

NMN supplementation and metabolic outcomes (VITALIZE)

  1. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224 to 1229. View Study
  2. Irie J, Inagaki E, Fujita M, et al. Effect of oral NMN on clinical parameters in healthy men. Endocrine Journal. 2020;67(2):153 to 160. View Study
  3. Yi L, Maier AB, Tao R, et al. Efficacy and safety of beta-NMN supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled trial. GeroScience. 2023;45(1):29 to 43. View Study
  4. Huang H. Efficacy and safety of Uthever NMN supplementation in middle-aged and older adults. Frontiers in Aging. 2022;3:851698. View Study

NMN transport and NAD+ metabolism (VITALIZE)

  1. Grozio A, Mills KF, Yoshino J, et al. SLC12A8 is a nicotinamide mononucleotide transporter. Nature Metabolism. 2019;1:362 to 370. View Study
  2. Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins. Annual Review of Nutrition. 2008;28:115 to 130. View Study

CD38 inhibition and NAD+ preservation (VITALIZE)

  1. Escande C, Nin V, Price NL, et al. Flavonoid apigenin is an inhibitor of the NAD+ ase CD38. Diabetes. 2013;62(4):1084 to 1093. View Study
  2. Ogura Y, Kitada M, Xu J, et al. CD38 inhibition by apigenin restores intracellular NAD+/NADH ratio and SIRT3 activity. Aging (Albany NY). 2020;12(12):11325 to 11336. View Study

Methylation support and NAD+ recycling (VITALIZE)

  1. Williams EG, et al. An introduction to systems genetics. Journal of Biological Chemistry. 2012. View Study
  2. Bhasin S, et al. NAD+ metabolism and the requirement for methylation support. Nature Metabolism. 2023. View Study
  3. Steenge GR, Verhoef P, Katan MB. Betaine supplementation lowers plasma homocysteine in healthy men and women. American Journal of Clinical Nutrition. 2001;74(1):136 to 138. View Study

Autophagy and cellular recycling (RENEW)

  1. Ohsumi Y. Discovery of autophagy genes and the cellular recycling pathway. Nobel Prize in Physiology or Medicine. 2016. Press release | Advanced information
  2. Rubinsztein DC, et al. Autophagy and aging. Cell (Review). View on PubMed
  3. Ma D, et al. Circadian control of autophagy: clock genes regulate daily autophagy rhythms. Proceedings of the National Academy of Sciences (PNAS). PMC | PubMed

EGCG, autophagy and antioxidant protection (RENEW)

  1. Zhou J, et al. EGCG increases autophagosome formation and autophagic flux via AMPK involvement. Journal of Nutritional Biochemistry. PubMed | PMC

Curcumin and inflammation balance (RENEW)

  1. McFarlin BK, et al. Longvida curcumin (400 mg/day) reduces rises in inflammatory and CK markers in a 4-day recovery model versus placebo (human study). Journal of Dietary Supplements. PubMed | PMC
  2. Nelson KM, et al. Curcumin formulation review: third-generation strategies (including SLCP/Longvida) improve systemic and free curcumin availability. Pharmaceutics. PMC
  3. Gota VS, et al. Longvida/SLCP human pharmacokinetics: free curcumin detectable in plasma; improved exposure versus conventional forms. Journal of Agricultural and Food Chemistry. PubMed

Astaxanthin and oxidative defense (RENEW)

  1. Zhang L, et al. Astaxanthin meta-analysis (2022): reductions in oxidative-stress and inflammation biomarkers (human studies). Nutrients. PubMed
  2. Yuan JP, et al. Astaxanthin meta-analysis (2020): antioxidant effects versus control; trend toward lower MDA. Marine Drugs. PubMed

Spermidine and cellular longevity (RENEW)

  1. Kiechl S, et al. Spermidine intake and mortality in the Bruneck cohort: higher dietary intake associated with lower mortality over approximately 20 years. American Journal of Clinical Nutrition. PubMed
  2. Madeo F, et al. Spermidine and aging: review. Levels decline with age; exogenous spermidine reverses age-associated cellular changes (preclinical and early clinical evidence). Aging (Albany NY). PMC

Circadian rhythm and evening light exposure

  1. Chang AM, et al. Evening light-emitting eReaders suppress melatonin, delay circadian timing, and reduce next-morning alertness. Proceedings of the National Academy of Sciences (PNAS). PubMed | PNAS

Senolytics and senescent cell clearance (RESET)

  1. Baker DJ, et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011;479(7372):232 to 236. View on PubMed
  2. Kirkland JL, Tchkonia T. Senolytic drugs: from discovery to translation. Journal of Internal Medicine. 2020;288(5):518 to 536. View Study
  3. Zhu Y, et al. Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors. Aging Cell. 2016;15(3):428 to 435. View Study

Human senolytic intervention studies (RESET)

  1. Justice JN, et al. Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label pilot study. EBioMedicine. 2019;40:554 to 563. View on PubMed
  2. Hickson LJ, et al. Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of dasatinib plus quercetin in individuals with diabetic kidney disease. EBioMedicine. 2019;47:446 to 456. View on PMC
  3. Nambiar A, et al. Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results from a randomized pilot trial. EBioMedicine. 2023. View on PubMed

Fisetin (RESET)

  1. Yousefzadeh MJ, et al. Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine. 2018;36:18 to 28. View on PubMed
  2. Khan N, et al. Fisetin: a dietary antioxidant for health promotion. Antioxidants and Redox Signaling. 2013;19(2):151 to 162. View Study
  3. AFFIRM Frailty Trial (ongoing). Fisetin in older adults. ClinicalTrials.gov NCT03675724

Quercetin and Quercefit (RESET)

  1. Di Pierro F, et al. Quercefit (quercetin phytosome): enhanced bioavailability (approximately 20x) and improvements in antioxidant and inflammation markers. Minerva Medica. 2019;110(7):524 to 533. View on PubMed
  2. Riva A, et al. Improved oral absorption of quercetin from quercetin phytosome in healthy subjects. European Journal of Drug Metabolism and Pharmacokinetics. 2019;44(2):169 to 177. View Study

Luteolin (RESET)

  1. Kou X, et al. Luteolin alleviates oxidative stress and cellular senescence via SIRT1/p53 pathway modulation. Free Radical Biology and Medicine. 2017;106:20 to 30. View on PubMed
  2. Luo Y, et al. Luteolin ameliorates neuroinflammation and memory impairment through microglial modulation. Frontiers in Aging Neuroscience. 2017;9:254. View on PubMed

Bioavailability enhancement across the system

  1. Singh A, et al. Enhanced oral bioavailability of quercetin with piperine co-administration: preclinical evidence. Pharmacognosy Magazine. 2017;13(Suppl 2):S250 to S256. View on PMC
  2. Shoba G, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica. 1998;64(4):353 to 356. View on PubMed
  3. Tripathi S, et al. Piperine as a bioenhancer: a review of preclinical and clinical pharmacokinetic evidence. European Journal of Drug Metabolism and Pharmacokinetics. 2022;47(2):127 to 141. View on PMC

Skin aging and cellular senescence

  1. Waaijer M, et al. The number of p16INK4a-positive cells is increased in aged human dermis. Aging Cell. 2012;11(4):722 to 725. View Study
  2. Pilkington S, et al. Senescent fibroblasts accumulate in human skin with aging and impair the tissue environment. Journal of Investigative Dermatology. 2021. View Study
  3. Wlaschek M, Scharffetter-Kochanek K. Senescent dermal fibroblasts and the aging skin extracellular matrix. Journal of Investigative Dermatology. 2021. View Study

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