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VITALIZE

Cellular Energy, Built to Be Measured.  

DAILY AM
1-month supply - 60 capsules

Supports all 4 stages of the NAD⁺ cycle for measurable cellular energy.

NAD⁺ powers how your cells generate energy, perform and recover.
By supporting all 4 stages of the cycle, VITALIZE helps you maintain and use NAD⁺ effectively, not just raise it.

The result: more consistent energy, clearer focus and stronger long-term vitality.

4-stages of the NAD⁺ cycle: Replenish → Protect → Recycle → Activate

Engineered System: 6 complementary ingredients, anchored by a 500 mg NAD⁺ precursor.

Energy: Delivers steadier cellular energy and daily stamina

Focus: Enhances mental clarity and performance

Units:
Made in Germany · 90-day guarantee · Free shipping from €150

Manufactured in Germany

Clinically studied ingredients

Third-Party Tested for Purity

Six-Ingredient NAD+ System

What to expect over time

Consistency compounds. Early shifts often show up within weeks. Deeper benefits build over months.

Timeline showing expected VITALIZE progress at month 1, month 3, and month 6 for energy, clarity, recovery, and endurance

1 MONTH

First signs

Energy feels steadier
Mental clarity improves

3 MONTHS

Performance builds

Stamina lasts longer
Recovery feels easier

6 MONTHS

Compounded gains

Enhanced cellular function

Improved clarity & endurance

NAD⁺: Your Cells’ Hidden Energy Reserve

Chart showing age-related decline in NAD⁺ levels from early adulthood to midlife

NAD⁺ powers every cell in your body
It’s your built-in cellular battery.

From your 30s onward, levels decline.
By midlife, they are often ~50% lower.
That’s like running your cells on half a battery.

When NAD⁺ drops, you may notice:
– Lower daily energy
– Slower recovery
– Reduced mental clarity
– Early changes in skin vitality

The good news:
NAD⁺ levels are modifiable. With consistent support, you can rebuild your cellular energy reserve over time.

Raising NAD⁺ isn’t just about adding more

Diagram showing how Cellaro VITALIZE supports NAD⁺ reserve by replenishing, preserving, and recycling NAD⁺, directing benefits to sirtuins and AMPK.

NAD⁺ naturally declines with age.

But raising NAD⁺ isn’t just about adding more.

It works through 4 essential stages.

VITALIZE supports each one:

Replenish. Preserve. Recycle. Activate.

When all four stages are supported, your cells can produce and use energy more efficiently, not just temporarily.

The result: steadier energy, clearer focus and stronger long-term vitality.

Proven to Increase NAD⁺ Levels

image with teal background representing energy showing nad+ test result increase of over 50%

Designed for measurable change.

In a four-week protocol, participants following the VITALIZE daily routine increased NAD⁺ levels by an average of over 50%.

This reflects how VITALIZE is built:
six complementary ingredients, each included at clinically relevant daily doses.

Rather than relying on a single compound, VITALIZE supports NAD⁺ production, preservation, recycling, and activation - aligning with how cellular energy actually works.

Our Ingredients

Clinically studied ingredients, precisely dosed and designed to work together.

Nicotinamide mononucleotide (NMN) ingredient supporting NAD⁺ production

Uthever® NMN 

Directly boosts NAD⁺ levels, the essential building block for cellular energy and repair. Clinically studied, >99% pure.

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Resveratrol polyphenol from grapes supporting cellular stress response pathways

Trans-Resveratrol 

Activates NAD⁺-dependent sirloins and supports AMPK signaling for efficient energy use and stress resilience.

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Apigenin flavonoid from chamomile supporting NAD⁺ preservation via CD38 modulation

ApiAge™ Apigenin

Helps temper CD38 (an NAD⁺-consuming enzyme) to support NAD⁺ availability and protect against cellular stress.

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Trimethylglycine from beetoot supports methylation balance during NAD⁺ metabolism

TMG

Supports NAD⁺ recycling by fueling the methylation cycle — helping maintain healthy NAD⁺ balance.

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Synergy Together: A Smarter Way to Support NAD⁺ Levels

Comparison chart showing VITALIZE versus single-ingredient NAD⁺ products and generic blends across key support pathways and transparency

Longevity insights for cellular energy

How to Raise NAD⁺ Levels

How to Raise NAD⁺ Levels

NAD⁺ helps power cellular energy and steady focus. Levels naturally decline with age, stress, and disrupted rhythms—so days feel heavier...
Read more

VITALIZE Frequently Asked Questions

Cellaro VITALIZE is a daily NAD⁺ support supplement designed to help maintain cellular energy, resilience, and metabolic function. It combines NMN with complementary compounds that support NAD⁺ production, recycling, and protection—so levels rise more efficiently and stay steadier across the day.

No. VITALIZE isn’t a stimulant and contains no caffeine. It supports cellular energy metabolism (via NAD⁺ pathways), which most people feel as steadier days, not a buzz or crash. You can still drink coffee; VITALIZE works on the cellular machinery that helps you run efficiently across the day.

NMN raises NAD⁺, but production is only part of the equation. Cellaro VITALIZE is designed as a multi-pathway system that supports NAD⁺ from several angles:

  • NMN to support NAD⁺ synthesis
  • Apigenin to help limit NAD⁺ breakdown by moderating CD38 activity
  • Resveratrol and pterostilbene to engage sirtuin-linked metabolic and repair signalling
  • TMG (trimethylglycine) to support methylation balance during sustained NAD⁺ turnover

By addressing synthesis, preservation, and downstream signalling together, VITALIZE helps reduce biological bottlenecks and supports steadier NAD⁺ levels across the day, rather than relying on a single precursor alone.

Take VITALIZE every morning, ideally at the same time. With breakfast is simplest; if you fast, take it with your first meal. Coffee is fine. A little dietary fat may aid comfort/absorption of fat-soluble polyphenols. Training and rest days are both VITALIZE days, consistency is the point.

Raising NAD⁺ is step one. VITALIZE is a multi-pathway system: precursor (NMN), support for NAD⁺ breakdown and recycling, and polyphenols that engage repair signaling. This helps remove bottlenecks for a quicker ramp and steadier levels across the day, rather than relying on a single precursor that only addresses NAD⁺ production.

We recommend 500 mg daily (2 capsules) for a robust start; many see clearer changes by ~8 weeks. After re-testing, some maintain at 250 mg (1 capsule); others, especially active or 40+—stay at 500 mg. New to NMN? Start with 1/day for 1–2 weeks, then move to 2/day.

IV drips can create a short-lived spike and are time-intensive/costly. VITALIZE aims to build and stabilise your own NAD⁺ daily, is easier to sustain, and fits real life. If you’re considering IVs, measure, don’t guess, using the NAD⁺ blood test before and after to compare.

VITALIZE is stimulant-free and generally well tolerated. Rarely, mild stomach discomfort occurs; taking with food can help. If you’re pregnant, breastfeeding, have a medical condition, or take prescription medicines (especially anticoagulants), review the ingredients with your clinician before use.

Yes. Take a baseline NAD⁺ blood test before starting, then re-test in 8–12 weeks under similar conditions. You’ll see your number, reference range, and change over time, so you can confirm impact and fine-tune your plan.

References

NAD⁺ biology, aging, and circadian regulation

  1. Imai S-I, Guarente L. NAD⁺ and sirtuins in aging and disease. Trends in Cell Biology. 2014;24(8):464–471. View on PubMed
  2. Nakahata Y, Sahar S, Astarita G, et al. Circadian control of the NAD⁺ salvage pathway by CLOCK–SIRT1. Science. 2009;324(5927):654–657. View Study
  3. Ramsey KM, Yoshino J, Brace CS, et al. Circadian clock feedback cycle through NAMPT-mediated NAD⁺ biosynthesis. Science. 2009;324(5927):651–654. View Study

Human NMN supplementation and metabolic outcomes

4. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224–1229.View Study
Clinical trial: NCT03151239

5. Irie J, Inagaki E, Fujita M, et al. Effect of oral NMN on clinical parameters in healthy men. Endocrine Journal. 2020;67(2):153–160. View Study

6. Yi L, Maier AB, Tao R, et al. Efficacy and safety of β-NMN supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled trial. GeroScience. 2023;45(1):29–43. View study
Clinical trial: NCT04823260

7. Huang H. Efficacy and safety of Uthever® NMN supplementation in middle-aged and older adults. Frontiers in Aging. 2022;3:851698.
View study
Clinical trial: NCT04228640

NMN transport and NAD⁺ metabolism

8 Grozio A, Mills KF, Yoshino J, et al. SLC12A8 is a nicotinamide mononucleotide transporter. Nature Metabolism. 2019;1:362–370. View study

9. Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD⁺ precursor vitamins. Annual Review of Nutrition. 2008;28:115–130. View Study

Apigenin, CD38 inhibition, and NAD⁺ preservation

10. Escande C, Nin V, Price NL, et al. Flavonoid apigenin is an inhibitor of the NAD⁺ase CD38. Diabetes. 2013;62(4):1084–1093. View Study

11. Ogura Y, Kitada M, Xu J, et al. CD38 inhibition by apigenin restores intracellular NAD⁺/NADH ratio and SIRT3 activity. Aging (Albany NY). 2020;12(12):11325–11336. View Study

Bioavailability enhancers (piperine)

12. Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine inhibits human P-glycoprotein and CYP3A4. Journal of Pharmacology and Experimental Therapeutics. 2002;302(2):645–650. View Study

Manufacturer data and disclosures

13. Business Wire. “Effepharm’s Uthever® NMN clinical trial: NAD⁺/NADH increased ~38% at 60 days.” June 7, 2022. View article