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RESET

Monthly cellular clean-up to support long-term cellular health

MONTHLY AM/PM
8 capsules — 2-day protocol (monthly)

Over time, senescent cells accumulate and disrupt healthy cellular function. RESET is a targeted monthly protocol designed to support cellular clean-up and promote long-term cellular resilience.

Senescent-cell clean-up reduces cellular burden.

Calms age-related inflammatory signals.

Supports long-term cellular renewal and resilience

Made in Germany · 90-day guarantee · Free shipping from €100
Cellaro RESET monthly senolytic supplement pouch for cellular clean-up and renewal
RESET Sale price€30,00 EUR

Made in Germany

Clinically studied ingredients

Third-Party Tested for Purity

Multi-Active Formulas

How RESET Works

Calm water background illustrating monthly pulsed approach to cellular reset and recovery

RESET is a simple 2-day monthly protocol that harnesses clinically studied senolytics to clear out lingering senescent cells.

TargetSenescence Pathways

Natural senolytics (fisetin, quercetin and luteolin) identify senescent cells that drive inflammation and aging without touching healthy cells

Clear – Support natural removal

These compounds work through complementary pathways that support the body’s clearance processes, helping reduce lingering cells.

ResetMake space for renewal

Once cleared, your body can regenerate healthier cells, supporting resilience, recovery, and long-term vitality.

Read: Senescence 101

Why Pulse? The Smarter Way to Reset your Cells

RESET uses short, focused pulses—two days at a time—to target lingering “zombie” cells while minimizing impact on healthy cells.

Monthly senolytic pulsing schedule showing standard and advanced RESET protocols over four weeks

Standard Protocol (monthly)
For ongoing cellular renewal and healthy aging
2 capsules AM + 2 capsules PM
2 consecutive days per month (8 capsules total)

Advanced Protocol (twice monthly)
For higher inflammation, heavy training, or high-stress lifestyles
2 capsules AM + 2 capsules PM
2 consecutive days, twice per month (16 capsules total)

The more senescent cells you have, the older your body behaves

Diagram showing senescent cells releasing inflammatory signals that affect neighboring healthy cells

Senescent cells—often called “zombie cells”—stop working properly but don’t die. They linger and release pro-inflammatory signals that stress nearby cells, like a moldy fruit spoiling the whole bowl.​​

Over time, this build-up (inflammaging) can drain energy, slow recovery, and show up in skin as lines and dullness. As it accumulates, it contributes to age-related decline.​​

Preclinical research suggests that reducing the burden of senescent cells may help restore tissue function.

​​RESET is a 2-day monthly pulse designed to support cellular clean-up.​

Timeline showing progressive senescent cell clearance and cellular renewal over one to six months

MONTH 1:

Clean-up starts

Senolytic support begins
Aged cells start clearing

MONTH 3:

Clearance progresses

Senescent load declines
Inflammatory tone calms

MONTH 6:

Long-term renewal

Healthier cell turnover

Aging-related signals slow

Our Ingredients

Clinically studied. Backed by science.

Illustration of strawberries whee fiseting comes from  representing a natural senolytic compound used to target senescent cells

Fisetin

RESET’s foundation senolytic — clinically studied to target senescent cells and support full-body cellular renewal.

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llustration of apples which quercetin comes from showing a bioavailable flavonoid supporting senescence and inflammation pathways

Quercetin

Quercefit® quercetin (phytosome) — higher absorption. Works alongside fisetin on inflammatory and oxidative pathways.

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Luteolin illustration representing a neuroprotective flavonoid supporting brain and cellular aging pathways

Luteolin

Neuroprotective flavonoid that completes RESET’s brain-to-body senolytic strategy — targeting neuroinflammation and aging.

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Black pepper extract illustration used to enhance absorption and bioavailability of senolytic compounds

Black Pepper Extract

Enhances absorption and bioavailability of key ingredients for stronger results.

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Smarter Together: Synergy in Monthly Cellular Renewal

Comparison chart showing multi-pathway RESET protocol versus single-ingredient senolytic supplements

Build Your Longevity Routine

Longevity Insights

RESET Frequently Asked Questions

Standard RESET (once monthly)

Best for ongoing cellular renewal and healthy aging.

This protocol involves a 2-day pulse once per month and is ideal for long-term maintenance.

Advanced RESET (twice monthly)

Designed for periods of higher demand, such as increased inflammation, heavy training, travel, poor sleep, or high-stress lifestyles.

This protocol involves two 2-day pulses per month, spaced about two weeks apart.

Both protocols use the same daily dose — only the frequency changes.

Celaro RESET is a short, monthly supplement protocol designed to support the body’s natural clearance of senescent (“aging”) cells. It uses a two-day pulse rather than daily dosing, aligning with how senescent cells accumulate over time and how the body recovers between clearance phases.

Senescent cells are worn-out cells that stop dividing but don’t die. They linger and release inflammatory signals that can disrupt nearby healthy cells. Over time they accumulate, slowing recovery and raising background cellular stress. Reducing that burden helps restore a healthier cellular environment so healthy cells can function more efficiently.

RESET uses pulsed senolytic support—periodic, short protocols—rather than daily low dosing. It combines research-informed amounts of fisetin, quercetin phytosome (Quercefit®), and luteolin, with piperine for absorption. The goal is targeted support during pulses, followed by recovery time between them, instead of constant exposure.

Senescent cells build up gradually over time. RESET is designed to be taken in short, higher-dose pulses that help cross the activity threshold needed to tag and clear these cells, followed by off-days that allow your body to recover and remodel.

For most people, RESET is used once or twice per month, depending on individual needs, lifestyle, and current physiological stress.

Start with one 2-day pulse per month for ongoing cellular renewal and healthy aging.

Some people choose two 2-day pulses per month, spaced about 12–14 days apart, during periods of higher demand such as increased inflammation, heavy training, travel, or high stress.

RESET is not designed for daily use. The pulse approach is intentional — it provides focused support, then gives your body time to do the work.

Many people begin with two pulses per month, then transition to one pulse per month as their baseline maintenance once they feel more balanced.

Always follow the label for exact dosing.

Many people start with the Advanced Protocol to support an initial deeper reset, then transition to the Standard Protocol for ongoing maintenance once they feel balanced.

RESET is intentionally flexible — your protocol does not need to be permanent.

Most users notice easier day-to-day recovery and less background “drag” within 4–8 weeks, with steadier effects after 2–3 months of monthly pulses. Responses vary by age, training load, sleep, and nutrition. Consistency—running the pulse on schedule—matters more than the exact day of the month.

Yes. RESET’s pulse approach can be used alongside most nutrition and lifestyle routines. Keep your other supplements consistent across baseline and follow-up periods so you can assess changes. If you take prescription medicines or have a medical condition, consult your clinician before use.

Not intended for individuals under 18. If you are pregnant, breastfeeding, have a medical condition, or take medications, speak with your clinician before use. Discontinue and contact support if you experience sensitivity. Always follow the label and do not exceed the recommended protocol.
Not recommended during active cancer treatment unless advised by a clinician.

RESET is stimulant-free and generally well tolerated. A small number of people report mild, transient stomach discomfort during pulse days—taking with food and adequate hydration can help. If you feel unwell, stop and consult your clinician. This is a food supplement, not a medical treatment.

RESET is designed to complement Cellaro’s daily routines. VITALIZE supports cellular energy and NAD⁺ pathways, RENEW supports nightly repair and autophagy, and RESET provides periodic cellular clean-up. Used together, they support different phases of cellular health without overlapping daily stress.

RESET and BOOST support skin health through different but complementary pathways.

RESET focuses on cellular clean-up by supporting the body’s clearance of senescent cells, which are known to contribute to chronic low-grade inflammation (“inflammaging”) that can affect skin quality over time. By reducing background cellular stress, RESET helps create a healthier environment for skin renewal.

BOOST is designed to directly support skin structure and appearance, providing targeted nutrients for collagen integrity, hydration, and barrier function.

Used together, RESET supports the cellular environment, while BOOST supports skin structure and visible resilience.

Yes. Intense training increases cellular stress, and senescent cells can accumulate in muscle and joint tissues. A monthly (or twice-monthly) pulse can support steadier recovery. If you have a hard training block or event, schedule pulses on lighter days. Always follow the product directions.

RESET is vegan-friendly (no animal-derived actives) and gluten-free to the best of our knowledge. It does not contain common allergens as ingredients; always check the label for the latest allergen statement. If you have specific intolerances, consult your clinician before use.

[1] Campisi J, d’Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nature Reviews Molecular Cell Biology. 2007;8(9):729–740. PubMed

[2] Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. The Journals of Gerontology: Series A. 2014;69(Suppl 1):S4–S9. PubMed

[3] Childs BG, et al. Senescent cells: an emerging target for diseases of ageing. Nature Reviews Drug Discovery. 2017;16(10):718–735. PubMed

[4] Baker DJ, et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011;479(7372):232–236. PubMed

[5] Yousefzadeh MJ, et al. Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine. 2018;36:18–28. PubMed

[6] Kirkland JL, Tchkonia T. Senolytic drugs: from discovery to translation. Journal of Internal Medicine. 2020;288(5):518–536. (Review on senolytics and intermittent dosing.)

[7] Justice JN, et al. Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label pilot study. EBioMedicine. 2019;40:554–563. PubMed

[8] Di Pierro F, et al. Quercefit® (quercetin Phytosome): enhanced bioavailability (~20×) and improvements in antioxidant and inflammation markers. Minerva Medica. 2019;110(7):524–533. PubMed

[9] Tripathi S, et al. Piperine as a bioenhancer: a review of preclinical and clinical pharmacokinetic evidence. European Journal of Drug Metabolism and Pharmacokinetics. 2022;47(2):127–141. PMC

[10] Shoba G, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica. 1998;64(4):353–356. PubMed

[11] Singh A, et al. Enhanced oral bioavailability of quercetin with piperine co-administration: preclinical evidence. Pharmacognosy Magazine. 2017;13(Suppl 2):S250–S256. PMC

[12] Bailey DG, et al. Resveratrol and piperine pharmacokinetics in humans: lack of interaction. Nutrients. 2021;13(2):428. PMC

[13] Kou X, et al. Luteolin alleviates oxidative stress and cellular senescence via SIRT1/p53 pathway modulation. Free Radical Biology & Medicine. 2016;106:20–30.
PubMed:https://pubmed.ncbi.nlm.nih.gov/27765636/

[14] Luo Y, et al. Luteolin ameliorates neuroinflammation and memory impairment through microglial modulation. Frontiers in Aging Neuroscience. 2017;9:254.
https://pubmed.ncbi.nlm.nih.gov/28860949/