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Microneedling aftercare

Microneedling Aftercare: What to Do After Treatment (Day 1 to Week 12)

The treatment creates the repair signal. Your body does the building. Microneedling aftercare isn't about what you apply to the surface. It's about what you give your skin from within.

The repair window

Microneedling doesn't build collagen.
It triggers your skin to do it.

When a needle creates a controlled puncture in the dermis, it triggers a repair cascade that runs for up to 12 weeks. What your skin constructs during that window - the density, organisation, and longevity of new collagen - depends on the environment it's working in. This is the window where internal support makes a difference.

Inflammation

Hours 0 to Day 4

The repair signal is sent. Immune cells flood the site. This phase should not be suppressed. It starts the cascade.

Proliferation

Weeks 1 to 6

Fibroblasts activate and begin synthesising new collagen, elastin, and hyaluronic acid. This is when raw materials matter most.

Remodelling

Weeks 4 to 12

Collagen fibres are reorganised, cross-linked, and matured. This phase determines how firm, dense, and lasting the results are.

The Cellaro Skin Renewal Duo — BOOST and RESET
The Skin Renewal Duo

One builds.
One defends.

Two supplements designed for the 12-week window microneedling opens. BOOST feeds the repair. RESET clears what blocks it.

Build BOOST

Daily collagen support. Supplies the dermal matrix nutrients your skin uses to rebuild during the remodelling window.

Defend RESET

Monthly cellular cleanup. Clears the senescent cells that accumulate after microneedling and suppress new collagen.

Shop the Skin Renewal Duo →
BOOST reaches the dermis via the bloodstream where collagen is built

Where results are built

Microneedling triggers the rebuild.
What you do next shapes the result.

Creams and serums act on the epidermis, the outer layer of skin. That's as far as they go. The barrier is doing its job.

Collagen, elastin, and hyaluronic acid are formed in the dermis, deeper in the skin, fed by the bloodstream.

BOOST travels via the bloodstream to the dermis, supplying the nutrients fibroblasts need to build collagen during the 12-week remodelling window. RESET clears the cellular environment those fibroblasts are working in.

Topicals don’t reach where this rebuilding happens.
That’s why they’re not enough on their own.
To support your results, you need to support your skin from within.

The hidden obstacle

What is sabotaging your microneedling results?

As skin ages, certain cells stop functioning normally but remain metabolically active. They release signals that break down existing collagen and disrupt the formation of new collagen during the repair process.

The more of these cells you have, the harder it is for your skin to capitalise on the 12-week window microneedling opens. Results become less predictable. Recovery takes longer. The structural improvements don't hold as well between sessions.

This is why RESET works

A plant-based formula that helps reduce this cellular burden before and between treatments. Taken as a 2-day pulse, once a month. That's it.

Inside the skin over time

20s 30s 40s 50s 60s 70s AGE Collagen Senescent cells

Dermal senescent cells rise as dermal collagen declines.
Adapted from Y. Ogata et al.

A cleaner cellular environment supports cleaner collagen remodelling.

BOOST — Key Actives

What BOOST delivers

Independent clinical results from BOOST's key actives. Measured without microneedling

+39% Elasticity
+44% Firmness
+40% Hydration
+34% Collagen synthesis Ex vivo, human dermal fibroblast model. SkinAx²™ Lift.

Randomized, controlled trial. Results measured at 8 weeks.

How to take it

One daily. One monthly.
That's the protocol.

BOOST

Take daily

2 capsules every morning

1

Start after your first treatment

2

2 capsules every morning — no food required

3

Continue for 12 weeks — the full remodelling window

RESET

2 days a month

2 capsules morning and 2 capsules evening for 2 days

1

Start your first pulse 1 week after treatment

2

Once a month for 3 months

3

Avoid taking within 7 days before or after any treatment

12 weeks Daily BOOST through the remodelling window
3x Monthly RESET pulses over 3 months
2 days That is all RESET takes each month
Inside BOOST

Three actives. One repair window.

Each ingredient was chosen for what it delivers during the 12-week remodelling period that microneedling triggers in the dermis.

SkinAx2 Lift grape polyphenol complex Collagen synthesis

SkinAx²™ Lift

+34% collagen synthesis in independent clinical testing

Microneedling activates fibroblasts, the cells that build new collagen. SkinAx²™ Lift supports the collagen and elastin synthesis those fibroblasts carry out during the remodelling window, when the quality of your results is being determined.

Learn more
REGGENERATE eggshell membrane complex Dermal matrix

REGGENERATE™

+44.7% Firmness
+39.3% Elasticity
+40% Hydration

Clinical trial, 300mg per day, 57 days

Microneedling activates the repair signal. What gets built during those 12 weeks depends on what materials are available in the dermis. REGGENERATE™ supplies the complete structural complex, collagen types I, V, and X, elastin, and hyaluronic acid, in native form so your skin has what it needs to amplify the results microneedling triggers.

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Ceramides skin barrier support Barrier recovery

Ceramides

Supports barrier recovery from within while the surface heals

Microneedling temporarily disrupts the skin barrier. Ceramides work from within to support its recovery, helping skin retain moisture, reduce sensitivity, and restore barrier integrity during the healing phase and beyond.

Learn more
Inside RESET

Clear the path. Let repair happen.

Senescent cells accumulate after microneedling and suppress new collagen production. RESET's senolytics clear them, so the repair environment stays productive.

Fisetin strawberry illustration Senolytic

Fisetin

The most potent flavonoid senolytic in research

Senescent cells build up at microneedling sites and actively suppress the fibroblasts around them. Fisetin selectively clears them, creating the cellular space new collagen production needs to take hold.

Learn more
Quercetin apple illustration Senolytic

Quercetin

The most widely studied senolytic compound

Works alongside Fisetin to target the inflammatory signals senescent cells release. Reducing this load keeps the repair environment clean and productive during the weeks when collagen remodelling is most active.

Learn more

Frequently Asked Questions

Microneedling triggers a repair process that continues for up to 8–12 weeks. While redness may fade within days, collagen production, organisation, and strengthening happen over a much longer period.

our skin goes through three phases:

  • Inflammation (Days 0–4): The repair signal is activated
  • Proliferation (Weeks 1–6): New collagen, elastin, and hyaluronic acid are produced
  • Remodelling (Weeks 4–12): Collagen fibres are strengthened and reorganised

This final phase determines how firm, smooth, and long-lasting your results are.

Immediately after treatment, avoid harsh actives, excessive sun exposure, and anything that disrupts healing. Long-term, the bigger mistake is relying only on surface-level care while the deeper rebuilding process is happening.

Topicals support the surface of the skin, but collagen and elastin are formed deeper in the dermis. This is why results depend not just on what you apply, but on how you support your skin internally during the rebuilding phase.

Collagen production depends on fibroblast activity and the availability of nutrients like amino acids, antioxidants, and structural components. Supporting your skin from within during the 8–12 week window helps optimise how collagen is formed, organised, and maintained.

Senescent cells are older, non-functioning cells that accumulate with age. Instead of supporting repair, they release inflammatory signals that can interfere with collagen production and skin regeneration.

Yes. If the cellular environment contains a higher burden of senescent cells, fibroblasts may not function optimally. Supporting cellular renewal and reducing this burden can help create a better environment for collagen remodelling.

Microneedling creates the signal for repair, but your body does the building. Supporting your skin internally helps provide the nutrients and cellular environment needed for stronger, more resilient results over time.

Some improvements appear within weeks, but the most meaningful changes develop gradually over 8–12 weeks as collagen matures. This is why consistent support during this period matters.

Post-microneedling care guide

How to take care of your skin after microneedling.

What you apply, eat, and avoid in the weeks after treatment shapes how much of the repair window your skin can actually use. Here is what the research supports, organised by timeframe.

First 24 hours Acute recovery
  • Avoid All makeup and foundation — your barrier is open and anything applied can enter the dermis directly
  • Avoid Heat: saunas, steam rooms, hot showers, and intense exercise — increased blood flow prolongs inflammation
  • Avoid Retinoids, AHAs, BHAs, and vitamin C serums — these will cause significant irritation on compromised skin
  • Do Cleanse gently with a mild, fragrance-free cleanser and lukewarm water
  • Do Apply a simple, fragrance-free moisturiser if recommended by your practitioner
  • Do Start BOOST — internal support begins working immediately
Days 2 to 6 Redness and sensitivity
  • Avoid Direct sun exposure without protection — new skin is highly susceptible to UV damage and pigmentation
  • Avoid Picking or peeling flaking skin — allow it to shed naturally to avoid post-inflammatory pigmentation
  • Avoid Alcohol
  • Do Apply SPF 50 mineral sunscreen every morning, even indoors near windows
  • Do Keep skin hydrated with gentle, non-active moisturisers
  • Do Continue BOOST daily
Days 7 to 14 Early repair
  • Do Reintroduce your regular skincare gradually — start with the gentlest actives first
  • Do Continue with BOOST
  • Do Prioritise sleep. The growth hormone secreted during deep sleep drives a significant portion of tissue repair
  • Do Eat enough protein. Amino acids are the direct building block of collagen
  • Avoid Exfoliating treatments until skin has fully normalised
  • Do Continue SPF daily — non-negotiable for the full 12 weeks if results matter to you
Weeks 1 to 12 The remodelling window
  • Do Take BOOST every morning — the remodelling phase needs a consistent supply of collagen precursors for the full 12 weeks
  • Do Take your monthly RESET pulse — 2 days on, timed at least 7 days from any procedure
  • Do Maintain SPF daily — UV exposure is the single biggest external factor degrading the collagen your skin is building
  • Remember Collagen maturation takes time and most visible improvement emerges at weeks 6 to 10
  • Do Reduce chronic stress where possible — elevated cortisol suppresses fibroblast activity and slows repair