A decaffeinated green tea catechin that supports cellular upkeep and inflammatory control.
Hallmarks supported: Proteostasis/Autophagy · Mitochondrial Function · Inflammatory Signaling
What is EGCG?
Epigallocatechin gallate (EGCG) is the most studied catechin found in green tea. It is a naturally occurring polyphenol involved in cellular housekeeping and inflammatory signaling.
In supplement form, EGCG provides a consistent, decaffeinated dose that supports cellular maintenance without stimulant effects.
How EGCG supports cellular processes
EGCG is best known for influencing pathways involved in cellular cleanup, oxidative balance, and inflammatory regulation. Rather than acting as a direct antioxidant alone, EGCG helps modulate signaling systems that govern how cells respond to everyday stress.
Research has examined EGCG’s interaction with pathways linked to autophagy, mitochondrial function, and inflammatory signaling. In practical terms, this supports a cleaner cellular environment and a calmer baseline for inflammatory responses, particularly when taken as part of an evening recovery routine.
Pathways and outcomes studied
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Supports cellular housekeeping and autophagy-related signaling
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Helps regulate inflammatory signaling pathways involved in tissue stress and recovery
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Contributes to mitochondrial resilience and metabolic efficiency
Why EGCG is included in RENEW
RENEW is designed to support overnight cellular repair and recovery. EGCG complements spermidine and curcumin by supporting cellular cleanup and inflammatory balance during the body’s natural repair window.
The EGCG used in RENEW is decaffeinated, allowing these benefits without stimulating the nervous system or interfering with sleep. Together with curcumin, spermidine, and astaxanthin, EGCG helps create an environment that supports cellular maintenance while you rest.
Dosage context
What RENEW provides
100 mg decaffeinated EGCG per evening (per 2-capsule serving).
What research uses
Human studies commonly explore EGCG intakes ranging from ~100–400 mg per day, depending on formulation, duration, and outcomes studied.
What this means for you
100 mg is selected as a supportive, well-tolerated amount that fits a nightly repair routine and works synergistically with other RENEW ingredients rather than acting as a standalone intervention.
Food vs. supplement
Green tea naturally contains EGCG, but amounts vary widely and are accompanied by caffeine. A standardized, decaffeinated extract provides a predictable dose that can be taken in the evening without affecting sleep or overstimulating the system.
Research snapshot
Cellular housekeeping and inflammatory signaling
EGCG has been widely studied for its role in pathways involved in cellular cleanup, oxidative balance, and inflammatory regulation.
Mitochondrial and metabolic support
Research suggests EGCG influences signaling networks linked to mitochondrial efficiency and cellular resilience under everyday stress.
FAQs
What is EGCG, in simple terms?
It’s the most studied polyphenol in green tea, known for supporting cellular cleanup and balanced inflammatory signaling.
Why use decaffeinated EGCG?
Caffeine can interfere with sleep and recovery. Decaffeinated EGCG allows cellular support without stimulating the nervous system, making it suitable for evening use.
Is EGCG an antioxidant?
EGCG does have antioxidant properties, but its primary role is supporting cellular signaling systems that regulate inflammation, stress responses, and cellular maintenance.

